Journal of Family and Community Medicine

ORIGINAL ARTICLE
Year
: 2020  |  Volume : 27  |  Issue : 1  |  Page : 8--14

Association between type 2 diabetes mellitus and Helicobacter pylori infection among Saudi patients attending National Guard Primary Health Care Centers in the Western Region, 2018


Abdullah M Alzahrani1, Areej A Al Zaidi2, Shahad M Alzahrani2, Sultana A Binmahfouz2, Fayssal M Farahat1 
1 Department of Family Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, King Abdulaziz Medical City, Jeddah, King Abdullah International Medical Research Center, Jeddah, Saudi Arabia
2 Department of Family Medicine, King Abdulaziz Medical City, Jeddah, Saudi Arabia

Correspondence Address:
Dr. Abdullah M Alzahrani
King Abdulaziz Medical City, King Abdullah International Medical Research Center, PO Box: 9515, Jeddah 21423
Saudi Arabia

BACKGROUND: Reports on Helicobacter pylori infection in diabetics are inconsistent and contradictory. This study attempted to identify the possible association between type 2 diabetes and H. pylori infection. MATERIALS AND METHODS: Following a cross-sectional design, participants were recruited from four National Guard Primary Health Care Centers in Jeddah City, Saudi Arabia. The study was conducted from December 2017 to November 2018. All participants underwent hemoglobin A1C (HbA1c) assessment and stool antigen test for H. pylori. RESULTS: A total of 212 type 2 diabetic patients aged 40 years or more, and 209 age-matched nondiabetic subjects were included in the study. About one-quarter of the diabetics and nondiabetics were positive for H. pylori (26.9% and 26.3%, respectively). There was no significant difference. The prevalence of H. pylori did not differ significantly in the type 2 diabetics, with regard to their age groups, gender, smoking status, body mass index, chronic diseases, their HbA1c level, duration of diabetes, or received type of therapy. The prevalence of H. pylori was significantly higher in overweight and obese nondiabetic subjects (P = 0.013). Obese participants in both groups had the highest prevalence of infection (57.9% and 54.5%, respectively, P = 0.038). CONCLUSION: About one-quarter of type 2 diabetics and nondiabetics in Jeddah City have H. pylori infection. There is no association between diabetes and H. pylori infection. H. pylori was significantly higher in patients with a high body mass index.


How to cite this article:
Alzahrani AM, Al Zaidi AA, Alzahrani SM, Binmahfouz SA, Farahat FM. Association between type 2 diabetes mellitus and Helicobacter pylori infection among Saudi patients attending National Guard Primary Health Care Centers in the Western Region, 2018.J Fam Community Med 2020;27:8-14


How to cite this URL:
Alzahrani AM, Al Zaidi AA, Alzahrani SM, Binmahfouz SA, Farahat FM. Association between type 2 diabetes mellitus and Helicobacter pylori infection among Saudi patients attending National Guard Primary Health Care Centers in the Western Region, 2018. J Fam Community Med [serial online] 2020 [cited 2020 Sep 29 ];27:8-14
Available from: http://www.jfcmonline.com/article.asp?issn=2230-8229;year=2020;volume=27;issue=1;spage=8;epage=14;aulast=Alzahrani;type=0