Year : 2019 | Volume
: 26 | Issue : 3 | Page : 187--192
Potentially inappropriate medications prescribed for older persons: A study from two teaching hospitals in Southern India
Arun N Bhatt1, Sherin S Paul1, Smitha Krishnamoorthy2, Basil T Baby1, Anna Mathew3, Balakrishnan R Nair4
1 Department of Community Medicine, Malankara Orthodox Syrian Church Medical College, Kolenchery, Kerala, India
2 Department of General Medicine, Amrita Institute of Medical Sciences, Kochi, Kerala, India
3 Department of Pharmacology, Malankara Orthodox Syrian Church Medical College, Kolenchery, Kerala, India
4 School of Medicine and Public Health, University of Newcastle, Newcastle, Australia
BACKGROUND: Potentially inappropriate medications (PIMs) are a major concern in geriatric care. The primary objective of our study was to assess the prevalence of PIMs prescribed for older persons attending outpatient setting of two teaching hospitals in Kerala state in South India, where the population is aging.
MATERIALS AND METHODS: A cross-sectional study was carried out in two teaching hospitals in Kerala. Four hundred consecutive outpatient medical records of patients aged 65 years and above were selected. The current medications of the patients were analyzed to identify PIMs by the Beers criteria 2015. Polypharmacy and hyperpolypharmacy were defined as 5–9 medications and ≥10 medications, respectively. Chi-square test was done to identify demographic variables and the pattern of health-care facility use associated with PIM prescription. Binary logistic regression was performed to adjust for confounding associations.
RESULTS: The prevalence of PIMs prescription was 34.0% (95% confidence interval: 29.4%–38.6%) and that of polypharmacy and hyperpolypharmacy was 45.8% and 13.5%, respectively. The common PIMs were proton-pump inhibitors, benzodiazepines, peripheral α-1 blockers, and first-generation antihistamines. Inpatient admission, visits to the emergency department, multiple diagnoses, polypharmacy, and hyperpolypharmacy were associated with PIM prescription (P < 0.05). Age, gender, number of outpatient visits, and specialist consultation were not associated with PIM prescription. Polypharmacy (adjusted odds ratio [aOR] =2.11) and hyperpolypharmacy (aOR = 5.55) had independent association with PIM prescription (P < 0.05).
CONCLUSION: PIM prescription appears to be common in teaching hospitals in Kerala. Polypharmacy and hyperpolypharmacy in older people should trigger a review of medication to reduce the use of PIM.
Dr. Sherin S Paul
Department of Community Medicine, Pushpagiri Institute of Medical Sciences and Research Centre, Thiruvalla, Kerala
|How to cite this article:|
Bhatt AN, Paul SS, Krishnamoorthy S, Baby BT, Mathew A, Nair BR. Potentially inappropriate medications prescribed for older persons: A study from two teaching hospitals in Southern India.J Fam Community Med 2019;26:187-192
|How to cite this URL:|
Bhatt AN, Paul SS, Krishnamoorthy S, Baby BT, Mathew A, Nair BR. Potentially inappropriate medications prescribed for older persons: A study from two teaching hospitals in Southern India. J Fam Community Med [serial online] 2019 [cited 2020 Jan 25 ];26:187-192
Available from: http://www.jfcmonline.com/article.asp?issn=2230-8229;year=2019;volume=26;issue=3;spage=187;epage=192;aulast=Bhatt;type=0