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ORIGINAL ARTICLE
Year : 2018  |  Volume : 25  |  Issue : 3  |  Page : 183-187

Pediatric sickle cell disease and obstructive sleep apnea: A cross-sectional study in a tertiary pediatric center in Saudi Arabia


1 Department of Pediatrics, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia
2 Department of Hematology Oncology, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia
3 Sleep disorders Center, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia
4 Division of Respiratory Medicine, Hospital for Sick Children; Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada

Correspondence Address:
Dr. Wadha Alotaibi
Department of Pediatrics, King Fahad Medical City, P. O. Box: 59046, Riyadh 11525
Kingdom of Saudi Arabia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jfcm.JFCM_153_17

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Objective: The aim of the study was to evaluate snoring and obstructive sleep apnea (OSA) in Saudi children with sickle cell disease (SCD). Materials and Methods: This cross-sectional study was conducted among children with SCD attending a hematology clinic were recruited. Demographics, clinical data, and sleep questionnaires were collected and overnight polysomnographies performed. Results: Seventy children (31 of whom were females) with SCD were included in the study. Their median (interquartile) age was 9 (6.5, 11) years and their body mass index z-score was −1.2 (−2.0, −0.4). Seventy-four percent of SCD patients snored and 32 (46%) had evidence of OSA (obstructive apnea-hypopnea index [OAHI] ≥2 events per hour of sleep), 13 of whom had moderate OSA (OAHI ≥5 and <10 events per hour of sleep) and 10 had severe OSA (OAHI ≥10 events per hour of sleep). Conclusion: Snoring and the proportion of OSA were high in children with SCD. This underlines the importance of screening for OSA in all children with SCD.


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Journal of Family and Community Medicine | Published by Wolters Kluwer - Medknow
Online since 05th September, 2010